What is Spravato® (esketamine)?
Spravato is an FDA-approved prescription nasal spray used under medical supervision to treat depression.
It may be recommended for adults experiencing:
- Treatment-resistant depression (after trying two or more antidepressants)
- Major depressive disorder with suicidal thoughts or actions

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Is Spravato the same as ketamine?
Not exactly.
Spravato (esketamine) is derived from ketamine but is specifically formulated as a nasal spray and administered in a controlled medical setting.
Because it is more targeted, it may be used at lower doses and can offer a different treatment experience than IV ketamine.
Will my insurance cover Spravato?
Spravato is covered by many major insurance plans.
Our team will:
- Verify your benefits
- Handle prior authorizations
- Help guide you through the process
We’re here to make this as simple as possible.
How do I get started?
Your first step is a consultation with one of our board-certified Psychiatric Mental Health Nurse Practitioners.
During this visit, we’ll review:
- Your symptoms
- Treatment history
- Whether Spravato may be a good fit
If you’ve received care elsewhere, bringing past records can be helpful.
Contact Us Today:
You don’t have to navigate this alone, we’re here to help.
Call 410-760-9079
Or contact us here to learn more
What should I expect during treatment?
Treatment takes place in a comfortable, private setting.
- You’ll be seated in a reclining chair
- Sessions include a 2-hour observation period
- You can bring items like headphones, a blanket, or a book
Many patients choose to rest quietly during treatment.
Are there side effects?
Like all medications, Spravato may cause side effects.
The most common include:
- Feeling disconnected or “out of body”
- Dizziness or nausea
- Drowsiness or fatigue
- Temporary changes in mood or perception
These effects typically occur shortly after treatment and resolve the same day.
What happens after treatment?
For your safety:
- You should not drive or operate machinery until the next day
- You’ll need a plan to get home (friend, family member, or transport service)
Our team will check in with you after your session to ensure you’re doing well.
Ready to take the next step?
You don’t have to navigate this alone—we’re here to help.
Call 410-760-9079 to speak with our patient support team
Or contact us here to learn more